| Name | Deductibility Code |
| Agape Food Pantry Inc. | -- |
| Benevolent Medication Program | -- |
| Bluefield College of Evangelism Inc. | -- |
| Brock Hughes Free Clinic Inc. | -- |
| Carroll House Operation Account Mt. Rogers Community Services Inc. | -- |
| Crossroads Shelter Inc. | -- |
| Edith Bolling Wilson Birthplace Foundation | 3 |
| Family Resources Center | -- |
| Friends of the Homestead | -- |
| Helping Overcome Povertys Existence Inc. | -- |
| Holston Conference Colleges Inc. | -- |
| Mountain View Smith Hollow Cemetary Association | 6 |
| New Covenant Fellowship Church | -- |
| Pendleton Construction Corporation Foundation | 4 |
| Presbyterian Childrens Home of the Highlands Inc. | -- |
| Return to Nature Inc. | -- |
| The Christmas Bear Inc. | -- |
| The Copper Crest Riding Therapy Program Inc. | -- |
| United Way of Wythe County Incorporated | -- |
| Wcch Holdings | -- |
| Wythe Arts Council Ltd. | -- |
| Wythe Conservation Network | -- |
| Wythe County Genealogical and Historical Association | -- |
| Wythe County Historical Society | -- |
| Wythe County Ministerial Association | -- |
| Wythe County Public Schools Foundation for Excellence Inc. | -- |
| Wythe County Rescue Squad Inc. | -- |
| Wythe United Soccer Club Inc. | -- |
| Wythe-Bland Animal Welfare League | -- |
| Wythe-Bland Community Foundation | -- |
| Wytheville Community College Educational Foundation Inc. | -- |
| Wytheville Community College Scholarship Foundation Inc. | -- |
| Wytheville Regional Housing Agency Inc. | -- |
| Wytheville Training School Cultural Center Inc. | -- |
| Wytheville Volunteer Fire Dept | -- |